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TrimethylamineNoxide induces vascular inflammation by activating the NLRP3 inflammasome through the SIRT3SOD2mtROS signaling pathway

Landscapes Chemical & Material Sciences (AREA) Organic Chemistry (AREA) Health & Medical Sciences (AREA) Epidemiology (AREA) Medicinal Chemistry (AREA) Pharmacology & Pharmacy (AREA) Emergency Medicine (AREA) Life Sciences & Earth Sciences (AREA) Animal Behavior & Ethology (AREA) General Health & Medical Sciences (AREA) Public Health (AREA) Veterinary Medicine (AREA) Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA) Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA) Abstract Stable and non-hygroscopic L-carnitine salts of organic acids are provided, each of which is present as a true complex salt, having the formula: wherein Z is acetate, propionate, or butyrate